Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Asthma causally affects the brain cortical structure: a Mendelian randomization study.

The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Sept 2025

Fu Tingting, Fu Xiao, Gao Jing, Zhao Shilong, Hu Chunling, Li Junlu, Xing Lihua

Abstract excerpt

OBJECTIVE: The potential causal relationship between asthma and brain structures remains uncertain. We performed a two-sample Mendelian randomization to investigate the causal effects of various asthma phenotypes - unspecified asthma, moderate-to-severe asthma, childhood-onset asthma, and adult-onset asthma (AOA) - on cerebral cortex structure. METHODS: We utilized phenotype data derived from genome-wide...

Read the complete abstract on PubMed

Topics

Humans
Asthma
Mendelian Randomization Analysis
Cerebral Cortex
Genome-Wide Association Study
Phenotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Adult

Magnetic Resonance Imaging

Child

Male

Female

Source

Identifiers

PMID: 40226995
DOI: 10.1080/02770903.2025.2493123

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Asthma causally affects the brain cortical structure: a Mendelian randomization study.PMID 40226995Read ↗

Association between asthma and changes in brain cortical structure: a Mendelian randomization study.Semantic proximity Read ↗

Causal effects of lung function on brain cortical and subcortical structure: a two-sample univariable and multivariable Mendelian Randomization study.Semantic proximity Read ↗

COPD, PRISm and lung function reduction affect the brain cortical structure: a Mendelian randomization study.Semantic proximity Read ↗

Unravelling the immune-brain connection: A Mendelian randomization study investigating the causal relationship between immune disease and cortical structureSemantic proximity Read ↗

Unspecified asthma, childhood-onset, and adult-onset asthma have different causal genes: a Mendelian randomization analysis.Semantic proximity Read ↗

Potential drug targets for asthma identified in the plasma and brain through Mendelian randomization analysis.Semantic proximity Read ↗

Mapping brain endophenotypes associated with idiopathic pulmonary fibrosis genetic riskSemantic proximity Read ↗

Association Between Environmental Factors and Asthma Using Mendelian Randomization: Increased Effect of Body Mass Index on Adult-Onset Moderate-to-Severe Asthma SubtypesSemantic proximity Read ↗

Mapping brain endophenotypes associated with idiopathic pulmonary fibrosis genetic riskSemantic proximity Read ↗

Causal relationships between cortical brain structural alterations and migraine subtypes: a bidirectional Mendelian randomization study of 2,347 neuroimaging phenotypes.Semantic proximity Read ↗

Genetic Overlap Between Global Cortical Brain Structure, C-Reactive Protein, and White Blood Cell Counts.Semantic proximity Read ↗

Mendelian randomization analyses support causal relationships between tinnitus of different stages and severity and structural characteristics of specific brain regions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.