Article
Characteristics of H3K27M-mutant diffuse gliomas with a non-midline location.
Journal of neuro-oncology - 1 Sept 2024
Guidara Souhir, Seyve Antoine, Poncet Delphine, Leonce Camille, Bringuier Pierre-Paul, McLeer Anne, Sturm Dominik, Cartalat Stéphanie, Picart Thiebaud, Ferrari Anthony, Hench Jürgen, Frank Stephan, Meyronet David, Ducray François, Barritault Marc
Abstract excerpt
PURPOSE: Diffuse midline gliomas (DMG) with H3K27 alterations (H3K27M-DMG) are a highly aggressive form of brain cancer. In rare cases, H3K27 mutations have been observed in diffuse non-midline gliomas (DNMG). It is currently unclear how these tumors should be classified. Herein, we analyze the characteristics of DNMG with H3K27M mutations. METHODS: We reviewed the clinical, radiological and histological...
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