Article
The impact of MICB mismatches in unrelated haematopoietic stem cell transplantation.
HLA - 1 Jun 2024
Amann Elisa Maria, Gowdavally Sowmya, Tsamadou Chrysanthi, Platzbecker Uwe, Sala Elisa, Wagner-Drouet Eva, Valerius Thomas, Kröger Nicolaus, Wulf Gerald, Einsele Hermann, Thurner Lorenz, Schaefer-Eckart Kerstin, Freitag Sebastian, Casper Jochen, Dürholt Mareike, Kaufmann Martin, Hertenstein Bernd, Klein Stefan, Ringhoffer Mark, Frank Sandra, Saal Teresa, Schmid-Möglich Amelie, Neuchel Christine, Schrezenmeier Hubert, Mytilineos Joannis, Fürst Daniel
Abstract excerpt
MICA polymorphisms have been associated with increased incidence of acute GvHD and adverse outcome in allogeneic haematopoietic stem cell transplantation (HSCT). MICB is another expressed member of MHC class I-related chain genes and its impact on HSCT outcome is yet to be fully defined. We typed a large cohort of patients and donors for MICB polymorphisms and investigated the impact of MICB matching on outcome...
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