Article
The MHC gamma block matching: Impact on unrelated hematopoietic stem cell transplantation outcome.
Human immunology - 1 Jan 2020
Maskalan Marija, Grubic Zorana, Serventi Seiwerth Ranka, Vrhovac Radovan, Mikulic Mirta, Burek Kamenaric Marija, Stingl Jankovic Katarina, Durakovic Nadira, Zunec Renata
Abstract excerpt
Matching for HLA-A, -B, -C, -DRB1, -DQB1 alleles is the gold standard in hematopoietic stem cell transplantation (HSCT). However, this is often not enough to prevent postransplantational complications. The HLA mismatches (MM) have been associated with higher risk of acute graft versus host disease (GvHD). Gamma block (GB) is located in central HLA region, between HLA-B/C and HLA-DRB/DQB blocks and contains many...
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