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Article

Bioinformatic Identification of TP53 Gene Mutation Hotspots in Colorectal Cancer.

International journal of molecular sciences - 15 Jun 2024

Kovács Zsolt, Sugimura Haruhiko, György Tamás Attila, Osvath Eva, Manirakiza Felix, Gurzu Simona

Abstract excerpt

Mutations and inactivation of the TP53 gene are frequently observed in various types of malignancies. Precise knowledge of the genetic structure and detection of mutation hotspots are crucial, as these indicate a high probability of developing cancer. The aim of our study was to perform the bioinformatic detection of mutation hotspots in the TP53 gene in patients diagnosed with malignant colon neoplasms using...

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Identifiers

PMID: 38928318
DOI: 10.3390/ijms25126612
PMCID: PMC11203433

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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