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Article

The longitudinal trajectory of CSF sTREM2: the alzheimer’s disease neuroimaging initiative

26 Jun 2024

Abstract excerpt

BACKGROUND: The soluble triggering receptor expressed on myeloid cells 2 (sTREM2) in cerebrospinal fluid (CSF) is considered a biomarker of microglia activity. The objective of this study was to investigate the trajectory of CSF sTREM2 levels over time and examine its association with sex. METHODS: A total of 1,017 participants from the Alzheimer's Disease Neuroimaging Initiative Study (ADNI) with at least one...

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PMID: 38926894
DOI: 10.1186/s13195-024-01506-8

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