Article
Associations of genetically predicted vitamin D status and deficiency with the risk of carotid artery plaque: a Mendelian randomization study.
Scientific reports - 26 Jun 2024
Meena Devendra, Dib Marie-Joe, Huang Jingxian, Smith Alexander, Huang Jian, Lota Amrit S, Prasad Sanjay K, Gill Dipender, Dehghan Abbas, Tzoulaki Ioanna
Abstract excerpt
Low concentrations of circulating 25-hydroxy-vitamin D are observationally associated with an increased risk of subclinical atherosclerosis and cardiovascular disease. However, randomized controlled trials have not reported the beneficial effects of vitamin D supplementation on atherosclerotic cardiovascular disease (ASCVD) outcomes. Whether genetically predicted vitamin D status confers protection against the...
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