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Article

Mendelian Randomization Studies Do Not Support a Role for Vitamin D in Coronary Artery Disease.

Circulation. Cardiovascular genetics - 1 Aug 2016

Manousaki Despoina, Mokry Lauren E, Ross Stephanie, Goltzman David, Richards J Brent

Abstract excerpt

BACKGROUND: Observational studies support a possible association between decreased vitamin D levels and risk of coronary artery disease (CAD); however, it remains unclear whether this relationship is causal. We aimed to evaluate whether genetically lowered vitamin D levels influence the risk of CAD using a Mendelian randomization approach. METHODS AND RESULTS: In this 2-stage Mendelian randomization study, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27418593
DOI: 10.1161/CIRCGENETICS.116.001396

Genes

CAD

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