Article
Genetically predicted circulating vitamin C in relation to cardiovascular disease.
European journal of preventive cardiology - 11 Jan 2022
Yuan Shuai, Zheng Ju-Sheng, Mason Amy M, Burgess Stephen, Larsson Susanna C
Abstract excerpt
AIM: We conducted a two-sample Mendelian randomization (MR) study to assess the associations of genetically predicted circulating vitamin C levels with cardiovascular diseases (CVDs). METHODS AND RESULTS: Ten lead single-nucleotide polymorphisms associated with plasma vitamin C levels at the genome-wide significance level were used as instrumental variables. Summary-level data for 15 CVDs were obtained from...
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