Article
Causal association of genetically determined circulating vitamin D metabolites and calcium with multiple sclerosis in participants of European descent.
European journal of clinical nutrition - 1 Apr 2023
Zhang Yan, Liu Haijie, Zhang Haihua, Han Zhifa, Wang Tao, Wang Longcai, Liu Guiyou
Abstract excerpt
BACKGROUND: Vitamin D is an important regulator of calcium. Mendelian randomization (MR) studies exclusively focused on the circulating total 25-hydroxyvitamin D (25(OH)D) as a biomarker of vitamin D status, and have found the causal association between 25(OH)D and the risk of multiple sclerosis (MS). However, it currently remains unclear about the causal association of the 25(OH)D subtypes including 25(OH)D3 and...
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