Article
Genetically predicted lipid traits mediate the association between folic acid and atherosclerosis.
Scientific reports - 17 Aug 2024
Qi Jie, Wu Haoyu, Chen Haichao, Han Wenqi
Abstract excerpt
Atherosclerosis (AS) is one of the most common causes of death from cardiovascular disease, and low folic acid (FA) levels have been reported to be strongly associated with an increased risk of AS. We aimed to obtain causal estimates of the association between FA and AS and to quantify the mediating role of known modifiable risk factors. Based on the largest genome-wide association study (GWAS) from the IEU Open...
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