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Restricting datasets to classifiable samples augments discovery of immune disease biomarkers

26 Jun 2024

Abstract excerpt

Immunological diseases are typically heterogeneous in clinical presentation, severity and response to therapy. Biomarkers of immune diseases often reflect this variability, especially compared to their regulated behaviour in health. This leads to a common difficulty that frustrates biomarker discovery and interpretation - namely, unequal dispersion of immune disease biomarker expression between patient classes...

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PMID: 38926389
DOI: 10.1038/s41467-024-49094-3

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