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Article

Expanding the understanding of biases in development of clinical-grade molecular signatures: a case study in acute respiratory viral infections.

PloS one - 1 Jan 2011

Lytkin Nikita I, McVoy Lauren, Weitkamp Jörn-Hendrik, Aliferis Constantin F, Statnikov Alexander

Abstract excerpt

BACKGROUND: The promise of modern personalized medicine is to use molecular and clinical information to better diagnose, manage, and treat disease, on an individual patient basis. These functions are predominantly enabled by molecular signatures, which are computational models for predicting phenotypes and other responses of interest from high-throughput assay data. Data-analytics is a central component of...

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PMID: 21673802
DOI: 10.1371/journal.pone.0020662
PMCID: PMC3105991

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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