Article
Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity
21 Jan 2008
Abstract excerpt
BACKGROUND: Investigations performed in mice and humans have acknowledged obesity as a low-grade inflammatory disease. Several molecular mechanisms have been convincingly shown to be involved in activating inflammatory processes and altering cell composition in white adipose tissue (WAT). However, the overall importance of these alterations, and their long-term impact on the metabolic functions of the WAT and on...
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