Article
Shared genetic and experimental links between obesity-related traits and asthma subtypes in UK Biobank.
The Journal of allergy and clinical immunology - 1 Feb 2020
Zhu Zhaozhong, Guo Yanjun, Shi Huwenbo, Liu Cong-Lin, Panganiban Ronald Allan, Chung Wonil, O'Connor Luke J, Himes Blanca E, Gazal Steven, Hasegawa Kohei, Camargo Carlos A, Qi Lu, Moffatt Miriam F, Hu Frank B, Lu Quan, Cookson William O C, Liang Liming
Abstract excerpt
BACKGROUND: Clinical and epidemiologic studies have shown that obesity is associated with asthma and that these associations differ by asthma subtype. Little is known about the shared genetic components between obesity and asthma. OBJECTIVE: We sought to identify shared genetic associations between obesity-related traits and asthma subtypes in adults. METHODS: A cross-trait genome-wide association study (GWAS)...
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