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Article

Targeted Next Generation Sequencing molecular profiling and its clinical application in adrenocortical cancer.

European journal of endocrinology - 2 Jul 2024

Cioppi Francesca, Cantini Giulia, Ercolino Tonino, Chetta Massimiliano, Zanatta Lorenzo, Nesi Gabriella, Mannelli Massimo, Maggi Mario, Canu Letizia, Luconi Michaela

Abstract excerpt

OBJECTIVE: Adrenal cortical carcinoma (ACC) is a rare malignancy with a generally poor but heterogeneous prognosis, especially depending on the tumour stage at diagnosis. Identification of somatic gene alterations combined with clinical/histopathological evaluation of the tumour can help improve prognostication. We applied a simplified targeted-Next-Generation Sequencing (NGS) panel to characterise the mutational...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38917236
DOI: 10.1093/ejendo/lvae077

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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