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Article

Blood-Based Next-Generation Sequencing in Adrenocortical Carcinoma.

The oncologist - 8 Jun 2022

Nazha Bassel, Zhuang Tony Z, Dada Hiba I, Drusbosky Leylah M, Brown Jacqueline T, Ravindranathan Deepak, Carthon Bradley C, Kucuk Omer, Goldman Jamie, Master Viraj A, Bilen Mehmet Asim

Abstract excerpt

BACKGROUND: Adrenocortical carcinoma (ACC) is a rare and heterogeneous malignancy with poor prognosis. We aimed to evaluate the feasibility of next-generation sequencing (NGS) testing of circulating cell-free tumor DNA (ctDNA) in patients with ACC, to characterize the genomic landscape of alterations, and to identify potential clinically actionable mutations. METHODS: Retrospective analysis of genomic data from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35462410
DOI: 10.1093/oncolo/oyac061
PMCID: PMC9177103

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