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Article

Molecular screening for a personalized treatment approach in advanced adrenocortical cancer.

The Journal of clinical endocrinology and metabolism - 1 Oct 2013

De Martino Maria Cristina, Al Ghuzlan Abir, Aubert Sebastien, Assié Guillaume, Scoazec Jean-Yves, Leboulleux Sophie, Do Cao Christine, Libè Rossella, Nozières Cécile, Lombès Marc, Pattou François, Borson-Chazot Francoise, Hescot Ségolène, Mazoyer Clement, Young Jacques, Borget Isabelle, Colao Annamaria, Pivonello Rosario, Soria Jean-Charles, Bertherat Jerome, Schlumberger Martin, Lacroix Ludovic, Baudin Eric

Abstract excerpt

CONTEXT: Adrenocortical cancer (ACC) is a rare cancer with poor prognosis and scant treatment options. In ACC, no personalized approach has emerged but no extensive molecular screening has been performed to date. OBJECTIVE: The objective of the study was to evaluate the presence of a large number of potentially targetable molecular events in a large cohort of advanced ACC. DESIGN, SETTING, AND PARTICIPANTS: We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23979958
DOI: 10.1210/jc.2013-2165

Genes

ATM
CTNNB1
CDK4
FGF9
FGFR1
FRS2

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