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Article

Molecular genomic profiling of adrenocortical cancers in clinical practice.

Surgery - 1 Jan 2021

Darabi Sourat, Braxton David R, Eisenberg Burton L, Demeure Michael J

Abstract excerpt

BACKGROUND: At presentation, 21% to 49% of patients with adrenocortical cancer have metastases. Standard chemotherapy has a 23% response rate. We assessed whether next generation sequencing could elucidate additional treatment options in refractory adrenocortical cancer. METHODS: Retrospective analysis using a commercial, 592-gene DNA-based panel was performed of next generation sequencing data from 94...

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Adrenal Cortex
Adrenal Cortex Neoplasms
beta Catenin
Datasets as Topic
DNA Repair
Drug Resistance, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Amplification

Precision Medicine

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PMID: 32709489
DOI: 10.1016/j.surg.2020.05.039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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