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Article

Targeted genomic analysis of 364 adrenocortical carcinomas.

Endocrine-related cancer - 16 Aug 2021

Pozdeyev Nikita, Fishbein Lauren, Gay Laurie M, Sokol Ethan S, Hartmaier Ryan, Ross Jeffrey S, Darabi Sourat, Demeure Michael J, Kar Adwitiya, Foust Lindsey J, Koc Katrina, Bowles Daniel W, Leong Stephen, Wierman Margaret E, Kiseljak-Vassiliades Katja

Abstract excerpt

Despite recent advances in elucidating molecular pathways underlying adrenocortical carcinoma (ACC), this orphan malignancy is associated with poor survival. Identification of targetable genomic alterations is critical to improve outcomes. The objective of this study was to characterize the genomic profile of a large cohort of patient ACC samples to identify actionable genomic alterations. Three hundred...

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Share to Adrenal and Paraganglionic Tumors
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Chromatin Remodeling and Cancer

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Source

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Identifiers

PMID: 34410225
DOI: 10.1530/ERC-21-0040
PMCID: PMC8384129

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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