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Assessing causal associations of bile acids with obesity indicators: A Mendelian randomization study

21 Jun 2024

Abstract excerpt

Maintaining a balanced bile acids (BAs) metabolism is essential for lipid and cholesterol metabolism, as well as fat intake and absorption. The development of obesity may be intricately linked to BAs and their conjugated compounds. Our study aims to assess how BAs influence the obesity indicators by Mendelian randomization (MR) analysis. Instrumental variables of 5 BAs were obtained from public genome-wide...

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PMID: 38905395
DOI: 10.1097/md.0000000000038610

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