Article
The causal associations of non-alcoholic fatty liver disease with blood pressure and the mediating effects of cardiometabolic risk factors: A Mendelian randomization study.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Nov 2023
Zhang Zhuxin, Li Le, Hu Zhao, Zhou Likun, Zhang Zhenhao, Xiong Yulong, Yao Yan
Abstract excerpt
BACKGROUND AND AIMS: Non-alcoholic fatty liver disease (NAFLD) is prevalent in hypertensive people, but the causal effect remains unclear. We employed Mendelian randomization (MR) approach to assess the causality between NAFLD and different blood pressure (BP) parameters. METHOD AND RESULTS: Instrumental variables for genetically predicted NAFLD, including chronically elevated serum alanine aminotransferase...
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