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Article

Identification of blood metabolites linked to the risk of cholelithiasis: a comprehensive Mendelian randomization study.

Hepatology international - 1 Dec 2022

Mi Jiarui, Jiang Lingjuan, Liu Zhengye, Wu Xia, Zhao Nan, Wang Yuanzhuo, Bai Xiaoyin

Abstract excerpt

BACKGROUND AND AIMS: Observational and Mendelian randomization (MR) studies have identified several modifiable risk factors of cholelithiasis. However, there is limited evidence about the causal effect of blood metabolites on the cholelithiasis risk. METHODS: To have a comprehensive understanding to causal relations between blood metabolites and cholelithiasis, for the primary discovery, we applied two MR methods...

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PMID: 35704268
DOI: 10.1007/s12072-022-10360-5

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