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Beta cell dedifferentiation in type 1 diabetes: sacrificing function for survival?

6 Jun 2024

Abstract excerpt

The pathogeneses of type 1 and type 2 diabetes involve the progressive loss of functional beta cell mass, primarily attributed to cellular demise and/or dedifferentiation. While the scientific community has devoted significant attention to unraveling beta cell dedifferentiation in type 2 diabetes, its significance in type 1 diabetes remains relatively unexplored. This perspective article critically analyzes the...

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PMID: 38904049
DOI: 10.3389/fendo.2024.1427723

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