Article
Human papillomavirus infection and biomarkers in sinonasal inverted papillomas: clinical significance and molecular mechanisms
16 Jun 2015
Abstract excerpt
BACKGROUND: The role of human papillomavirus (HPV) in sinonasal inverted papillomas (IPs) is controversial. Determining the prevalence of HPV infection and its impact on the molecular biology of these tumors is critical to characterizing its role in the pathogenesis of IPs. METHODS: A total of 112 paraffin-embedded IPs from 90 patients were studied. A tissue microarray was constructed and stained for p16, p53,...
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