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Article

Pattern of Expression of Cell Cycle–related Proteins in Malignant Transformation of Sinonasal Inverted Papilloma

1 Mar 2011

Abstract excerpt

BACKGROUND: It has been suggested that sinonasal inverted papilloma (IP) can progress to squamous cell carcinoma (SCC); however, mechanisms of malignant transformation are not fully understood. This study investigated alterations in the expression of cell cycle-related proteins in a multistep process of malignant transformation of IPs. METHODS: The expression of cell cycle-related proteins, including p53, p21,...

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PMID: 21679505
DOI: 10.2500/ajra.2011.25.3566

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