Article
New mutations affecting induced mutagenesis in yeast.
Mutation research - 1 Jan 2000
Lawrence C W, Krauss B R, Christensen R B
Abstract excerpt
Previously isolated mutations in baker's yeast, Saccharomyces cerevisiae, that impair induced mutagenesis were all identified with the aid of tests that either exclusively or predominantly detect base-pair substitutions. To avoid this bias, we have screened 11 366 potentially mutant clones for UV-induced reversion of the frameshift allele, his4-38, and have identified 10 mutants that give much reduced yields of...
Topics
- Arginine
- Cell Cycle
- DNA, Fungal
- Genes, Fungal
- Histidine
- Isoleucine
- Mutagenicity Tests
- Mutation
- Saccharomyces cerevisiae
- Ultraviolet Rays