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Article

Genetic Alterations of SMYD4 in Solid Tumors Using Integrative Multi-Platform Analysis.

International journal of molecular sciences - 31 May 2024

Olivera Santana Brunna Letícia, de Loyola Mariana Braccialli, Gualberto Ana Cristina Moura, Pittella-Silva Fabio

Abstract excerpt

SMYD4 is a member of the SMYD family that has lysine methyltransferase function. Little is known about the roles of SMYD4 in cancer. The aim of this study is to investigate genetic alterations in the SMYD4 gene across the most prevalent solid tumors and determine its potential as a biomarker. We performed an integrative multi-platform analysis of the most common mutations, copy number alterations (CNAs), and mRNA...

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Share to Biomarkers, Tumor
Share to DNA Copy Number Variations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Histone-Lysine N-Methyltransferase

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Source

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Identifiers

PMID: 38892284
DOI: 10.3390/ijms25116097
PMCID: PMC11172816

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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