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Variant level heritability estimates of type 2 diabetes in African Americans.

Scientific reports - 18 Jun 2024

Armstrong Nicole D, Patki Amit, Srinivasasainagendra Vinodh, Ge Tian, Lange Leslie A, Kottyan Leah, Namjou Bahram, Shah Amy S, Rasmussen-Torvik Laura J, Jarvik Gail P, Meigs James B, Karlson Elizabeth W, Limdi Nita A, Irvin Marguerite R, Tiwari Hemant K

Abstract excerpt

Type 2 diabetes (T2D) is caused by both genetic and environmental factors and is associated with an increased risk of cardiorenal complications and mortality. Though disproportionately affected by the condition, African Americans (AA) are largely underrepresented in genetic studies of T2D, and few estimates of heritability have been calculated in this race group. Using genome-wide association study (GWAS) data...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38890458
DOI: 10.1038/s41598-024-64711-3
PMCID: PMC11189523

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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