Article
Insights into the genetic susceptibility to type 2 diabetes from genome-wide association studies of glycaemic traits.
Current diabetes reports - 1 Jan 2014
Marullo Letizia, El-Sayed Moustafa Julia S, Prokopenko Inga
Abstract excerpt
Over the past 8 years, the genetics of complex traits have benefited from an unprecedented advancement in the identification of common variant loci for diseases such as type 2 diabetes (T2D). The ability to undertake genome-wide association studies in large population-based samples for quantitative glycaemic traits has permitted us to explore the hypothesis that models arising from studies in non-diabetic...
Topics
- Blood Glucose
- Diabetes Mellitus, Type 2
- Genetic Loci
- Genetic Predisposition to Disease
- Genetic Variation
- Genome-Wide Association Study
- Glucose Tolerance Test
- Glycated Hemoglobin
- Humans
- Phenotype
