Article
African ancestry and its correlation to type 2 diabetes in African Americans: a genetic admixture analysis in three U.S. population cohorts.
PloS one - 1 Jan 2012
Cheng Ching-Yu, Reich David, Haiman Christopher A, Tandon Arti, Patterson Nick, Selvin Elizabeth, Elizabeth Selvin, Akylbekova Ermeg L, Brancati Frederick L, Coresh Josef, Boerwinkle Eric, Altshuler David, Taylor Herman A, Henderson Brian E, Wilson James G, Kao W H Linda
Abstract excerpt
The risk of type 2 diabetes is approximately 2-fold higher in African Americans than in European Americans even after adjusting for known environmental risk factors, including socioeconomic status (SES), suggesting that genetic factors may explain some of this population difference in disease risk. However, relatively few genetic studies have examined this hypothesis in a large sample of African Americans with...
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