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Article

Effects of Genetic Risk on Incident Type 2 Diabetes and Glycemia: The T2D-GENE Lifestyle Intervention Trial.

The Journal of clinical endocrinology and metabolism - 18 Dec 2024

Lankinen Maria Anneli, Nuotio Petrus, Kauppinen Susanna, Koivu Noora, Tolonen Ulla, Malkki-Keinänen Katriina, Oravilahti Anniina, Kuulasmaa Teemu, Uusitupa Matti, Schwab Ursula, Laakso Markku

Abstract excerpt

CONTEXT: Lifestyle intervention prevents or delays type 2 diabetes (T2D) in subjects at a high risk of T2D. However, it is not known whether genetic variants modify the effect on incident T2D during lifestyle intervention. OBJECTIVE: To investigate whether a low or high genetic risk has effects on incident T2D in a group-based lifestyle intervention study. METHODS: The T2D-GENE trial involved 973 men from the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38888187
DOI: 10.1210/clinem/dgae422
PMCID: PMC11651687

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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