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Elucidating the function of STING in systemic lupus erythematosus through the STING Goldenticket mouse mutant

17 Jun 2024

Abstract excerpt

Abstract The complexity of systemic lupus erythematosus (SLE) arises from intricate genetic and environmental interactions, with STING playing a pivotal role. This study aims to comprehend the function of STING using the pristane-induced lupus (PIL) model in Sting missense mutant mice (Goldenticket or StingGt), which contrasts with previous research using Sting knockout mice. Investigating two-month-old StingGt...

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PMID: 38886451
DOI: 10.1038/s41598-024-64495-6

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