Article
DNA Mutational and Copy Number Variation Profiling of Primary Craniofacial Osteosarcomas by Next-Generation Sequencing.
Head and neck pathology - 17 Jun 2024
Zhu Gord Guo, Lu Chuanyong, Petrovic Ivana, Nafa Khedoudja, Chen Wen, Syed Aijazuddin, Rana Satshil, Klein Michael J, Huang Sinchun, Wang Lu, Tap William D, Ghossein Ronald A, Shah Jatin, Hameed Meera R
Abstract excerpt
BACKGROUND: Craniofacial osteosarcomas (CFOS) are uncommon malignant neoplasms of the head and neck with different clinical presentation, biological behavior and prognosis from conventional osteosarcomas of long bones. Very limited genetic data have been published on CFOS. METHODS: In the current study, we performed comprehensive genomic studies in 15 cases of high-grade CFOS by SNP array and targeted next...
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