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[Mutation characteristics of osteosarcoma: a single center study of 64 cases using next-generation sequencing].

Zhonghua bing li xue za zhi = Chinese journal of pathology - 8 Apr 2023

Gao D L, Dong R F, Liu W F, Gong L H, Xu H R, Niu X H, Ding Y

Abstract excerpt

Objective: To investigate the distribution and characteristics of gene mutations in osteosarcoma, and to analyze the frequency and types of detectable mutations, and to identify potential targets for individualized treatment of osteosarcoma. Methods: The fresh tissue or paraffin-embedded tissue samples of 64 cases of osteosarcoma that were surgically resected or biopsied and then subject to next generation...

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PMID: 36973198
DOI: 10.3760/cma.j.cn112151-20221030-00902

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