Article
Interleukin 17 gene polymorphism is associated with anti-aquaporin 4 antibody-positive neuromyelitis optica in the Southern Han Chinese--a case control study.
Journal of the neurological sciences - 15 Mar 2012
Wang Honghao, Zhong Xiaonan, Wang Kai, Qiu Wei, Li Jin, Dai Yongqiang, Hu Xueqiang
Abstract excerpt
BACKGROUND: Interleukin 17 (IL-17) plays an important role in many autoimmune diseases including neuromyelitis optica (NMO) and multiple sclerosis (MS), which are inflammatory demyelinating diseases of the central nervous system. A large number of non-HLA single nucleotide polymorphisms have been reported to increase the risk of MS. However, their effects on NMO have been less well studied. METHODS: Fifty-two...
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