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Article

Impact of genetic polymorphisms in the interleukin-18 and interleukin-21 genes on the risk and clinical outcomes of multiple sclerosis.

BMC neurology - 25 May 2026

Bakr Noha M, Hashim Noha A, El-Eshmawy Mohamed Adel, El-Baz Hatim A

Abstract excerpt

BACKGROUND: This study was designed to investigate the association of IL-18-137G/C (rs187238) and IL-21-1472G/T (rs2055979) single nucleotide polymorphisms (SNPs) with the risk of MS, the disease progression, and related clinical features. METHODS: In this study, 271 Egyptian individuals participated, including 131 MS cases (relapsing-remitting (RR-MS) cases [N = 99], and progressive MS cases [N = 32]) and 140...

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PMID: 42185985
DOI: 10.1186/s12883-026-04869-7
PMCID: PMC13220706

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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