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Induction and antiviral activity of ferret myxovirus resistance (Mx) protein 1 against influenza A viruses

12 Jun 2024

Abstract excerpt

Myxovirus resistance (Mx) proteins are products of interferon stimulated genes (ISGs) and Mx proteins of different species have been reported to mediate antiviral activity against a number of viruses, including influenza A viruses (IAV). Ferrets are widely considered to represent the 'gold standard' small animal model for studying pathogenesis and immunity to human IAV infections, however little is known...

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PMID: 38866913
DOI: 10.1038/s41598-024-63314-2

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