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Bat-borne H9N2 influenza virus evades MxA restriction and exhibits efficient replication and transmission in ferrets

25 Apr 2024

Abstract excerpt

Influenza A viruses (IAVs) of subtype H9N2 have reached an endemic stage in poultry farms in the Middle East and Asia. As a result, human infections with avian H9N2 viruses have been increasingly reported. In 2017, an H9N2 virus was isolated for the first time from Egyptian fruit bats (Rousettus aegyptiacus). Phylogenetic analyses revealed that bat H9N2 is descended from a common ancestor dating back centuries...

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PMID: 38664395
DOI: 10.1038/s41467-024-47455-6

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