Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quantitative efficacy paradigms of the influenza clinical drug candidate EIDD-2801 in the ferret model.

Translational research : the journal of laboratory and clinical medicine - 1 Apr 2020

Toots Mart, Yoon Jeong-Joong, Hart Michael, Natchus Michael G, Painter George R, Plemper Richard K

Abstract excerpt

Seasonal influenza viruses cause major morbidity and mortality worldwide, threatening in particular older adults and the immunocompromised. Two classes of influenza therapeutics dominate current disease management, but both are compromised by pre-existing or rapidly emerging viral resistance. We have recently reported a novel ribonucleoside analog clinical candidate, EIDD-2801, that combines potent antiviral...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytidine
Share to Dogs

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Viral

Share to Ferrets

Share to Hydroxylamines

Share to Influenza A virus

Share to Influenza, Human

Share to Madin Darby Canine Kidney Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 31945316
DOI: 10.1016/j.trsl.2019.12.002
PMCID: PMC7568909

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quantitative efficacy paradigms of the influenza clinical drug candidate EIDD-2801 in the ferret model.PMID 31945316Read ↗

Assessment of the efficacy of the neuraminidase inhibitor oseltamivir against 2009 pandemic H1N1 influenza virus in ferrets.Semantic proximity Read ↗

4’-Fluorouridine mitigates lethal infection with pandemic human and highly pathogenic avian influenza virusesSemantic proximity Read ↗

Cloned Defective Interfering Influenza Virus Protects Ferrets from Pandemic 2009 Influenza A Virus and Allows Protective Immunity to Be EstablishedSemantic proximity Read ↗

Paxlovid-like nirmatrelvir/ritonavir fails to block SARS-CoV-2 transmission in ferretsSemantic proximity Read ↗

An Orally Available, Small-Molecule Polymerase Inhibitor Shows Efficacy Against a Lethal Morbillivirus Infection in a Large Animal ModelSemantic proximity Read ↗

Neuraminidase Mutations Conferring Resistance to Oseltamivir in Influenza A(H7N9) Viruses.Semantic proximity Read ↗

Interactions of oseltamivir-sensitive and -resistant highly pathogenic H5N1 influenza viruses in a ferret model.Semantic proximity Read ↗

Sequencing, Annotation, and Characterization of the Influenza Ferret InfectomeSemantic proximity Read ↗

Influenza infection in ferrets with SARS-CoV-2 infection historySemantic proximity Read ↗

Influenza A and B viruses with reduced baloxavir susceptibility display attenuated in vitro fitness but retain ferret transmissibilitySemantic proximity Read ↗

Oseltamivir-Resistant Pandemic A/H1N1 Virus Is as Virulent as Its Wild-Type Counterpart in Mice and FerretsSemantic proximity Read ↗

Induction and antiviral activity of ferret myxovirus resistance (Mx) protein 1 against influenza A virusesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.