Article
Association of TNF-α 308G/A and LEPR Gln223Arg Polymorphisms with the Risk of Type 2 Diabetes Mellitus.
Genes - 27 Dec 2021
Trapali Maria, Houhoula Dimitra, Batrinou Anthimia, Kanellou Anastasia, Strati Irini F, Siatelis Argyris, Halvatsiotis Panagiotis
Abstract excerpt
The objective of the present study was to identify the association of the TNF-α- 308G/A and leptin receptor (LEPR) Gln223Arg polymorphisms with the risk of development of type 2 diabetes mellitus (T2DM). METHODS: A total of 160 volunteers were studied: 108 with T2DM and 52 participants as control, who served as the control group. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) for...
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