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Article

Comprehensive Proteogenomic Profiling Reveals the Molecular Characteristics of Colorectal Cancer at Distinct Stages of Progression.

Cancer research - 4 Sept 2024

Li Lingling, Jiang Dongxian, Liu Hui, Guo Chunmei, Zhang Qiao, Li Xuedong, Chen Xiaojian, Chen Zheqi, Feng Jinwen, Tan Subei, Huang Wen, Huang Jie, Xu Chen, Liu Chen-Ying, Yu Wei, Hou Yingyong, Ding Chen

Abstract excerpt

Colorectal cancer is the second most common malignant tumor worldwide. Analysis of the changes that occur during colorectal cancer progression could provide insights into the molecular mechanisms driving colorectal cancer development and identify improved treatment strategies. In this study, we performed an integrated multiomic analysis of 435 trace tumor samples from 148 patients with colorectal cancer, covering...

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Source

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Identifiers

PMID: 38861363
DOI: 10.1158/0008-5472.CAN-23-1878
PMCID: PMC11372369

Genes

BRAF
DDX5
KRAS
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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