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Molecular pathological classification of colorectal cancer—an update

1 Feb 2024

Abstract excerpt

Colorectal cancer (CRC) has a broad range of molecular alterations with two major mechanisms of genomic instability (chromosomal instability and microsatellite instability) and has been subclassified into 4 consensus molecular subtypes (CMS) based on bulk RNA sequence data. Here, we update the molecular pathological classification of CRC with an overview of more recent bulk and single-cell RNA data analysis for...

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PMID: 38319359
DOI: 10.1007/s00428-024-03746-3

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