Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeting HIF-1α in sickle cell disease and cancer: unraveling therapeutic opportunities and risks

3 May 2024

Abstract excerpt

INTRODUCTION: HIF-1α, a key player in medical science, holds immense significance in therapeutic approaches. This review delves into its complex dynamics, emphasizing the delicate balance required for its modulation. HIF-1α stands as a cornerstone in medical research, its role extending to therapeutic strategies. This review explores the intricate interplay surrounding HIF-1α, highlighting its critical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Hemoglobin structure and function
Share to Hemoglobinopathies and Related Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38861226
DOI: 10.1080/14728222.2024.2367640

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeting HIF-1α in sickle cell disease and cancer: unraveling therapeutic opportunities and risksPMID 38861226Read ↗

Systematic and comprehensive insights into HIF-1 stabilization under normoxic conditions: implications for cellular adaptation and therapeutic strategies in cancerSemantic proximity Read ↗

Hypoxia-inducible factor in cancer: from pathway regulation to therapeutic opportunitySemantic proximity Read ↗

Hypoxia signaling in human diseases and therapeutic targetsSemantic proximity Read ↗

Hypoxia Signaling in Cancer: From Basics to Clinical PracticeSemantic proximity Read ↗

Breakthrough science: hypoxia-inducible factors, oxygen sensing, and disorders of hematopoiesisSemantic proximity Read ↗

Expression of hypoxia-inducible factor 1: mechanisms and consequencesSemantic proximity Read ↗

Hypoxia-inducible factors: cancer progression and clinical translationSemantic proximity Read ↗

HIF-1: mediator of physiological and pathophysiological responses to hypoxiaSemantic proximity Read ↗

HIF-1 — A BIG CHAPTER IN THE CANCER TALESemantic proximity Read ↗

HIF3α: the little we know.Semantic proximity Read ↗

Investigating hypoxia-inducible factor signaling in cancer: Mechanisms, clinical implications, targeted therapeutic strategies, and resistanceSemantic proximity Read ↗

Hypoxia-inducible transcription factors: architects of tumorigenesis and targets for anticancer drug discoverySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.