Article
HIF3α: the little we know.
The FEBS journal - 1 Mar 2016
Ravenna Linda, Salvatori Luisa, Russo Matteo A
Abstract excerpt
Hypoxia-inducible factors (HIFs) are key regulators of the transcriptional response to hypoxic stress. Three inducible isoforms of HIF are present in mammals. HIF1α and HIF2α are the best characterized and structurally similar isoforms, while HIF3α is the most distantly related and is less studied. The HIF3α gene undergoes complex regulation and produces a large number of long and short mRNA splice variants,...
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