Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Generation of novel respiratory syncytial virus vaccine candidate antigens that can induce high levels of prefusion-specific antibodies.

Journal of bioscience and bioengineering - 1 Aug 2024

Matsuyama-Ito Rima, Hogiri Tomoharu, Kishida Hiroyuki, Takedomi Kei, Okada Okimasa, Nishizawa Akitoshi, Higashi-Nakatani Sakiko, Omasa Takeshi

Abstract excerpt

Respiratory syncytial virus (RSV) infection is an acute respiratory infection caused by RSV. It occurs worldwide, and for over 50 years, several attempts have been made to research and develop vaccines to prevent RSV infection; effective preventive vaccines are eagerly awaited. The RSV fusion (F) protein, which has gained attention as a vaccine antigen, causes a dynamic structural change from the preF to postF...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Neutralizing
Share to Antibodies, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antigens, Viral

Share to Epitopes

Share to Respiratory Syncytial Virus, Human

Share to Respiratory Syncytial Virus Infections

Share to Respiratory Syncytial Viruses

Share to Viral Fusion Proteins

Source

Identifiers

PMID: 38851988
DOI: 10.1016/j.jbiosc.2024.05.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Generation of novel respiratory syncytial virus vaccine candidate antigens that can induce high levels of prefusion-specific antibodies.PMID 38851988Read ↗

A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism.Semantic proximity Read ↗

Alternative conformations of a major antigenic site on RSV FSemantic proximity Read ↗

Flexible RSV prefusogenic fusion glycoprotein exposes multiple neutralizing epitopes that may collectively contribute to protective immunitySemantic proximity Read ↗

A foldon-free prefusion F trimer vaccine for respiratory syncytial virus to reduce off-target immune responsesSemantic proximity Read ↗

Rational design of uncleaved prefusion-closed trimer vaccines for human respiratory syncytial virus and metapneumovirus.Semantic proximity Read ↗

Amino Acid Substitutions in the Fusion Protein of Respiratory Syncytial Virus in Fukushima, Japan, During 2008–2023 and Their EffectsSemantic proximity Read ↗

The Cumulative Variations of Respiratory Syncytial Virus Fusion Protein (F) in Ten Consecutive Years in ChinaSemantic proximity Read ↗

Functional implications of respiratory syncytial virus F sequence variability: a comparative analysis using contemporary RSV isolatesSemantic proximity Read ↗

Rational design of respiratory syncytial virus dimeric F-subunit vaccines in protein and mRNA formsSemantic proximity Read ↗

Emergence of new antigenic epitopes in the glycoproteins of human respiratory syncytial virus collected from a US surveillance study, 2015–17Semantic proximity Read ↗

Mutating a flexible region of the RSV F protein can stabilize the prefusion conformation.Semantic proximity Read ↗

Phylodynamics and molecular epidemiology of the respiratory syncytial virus fusion protein in China.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.