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Article

Associations of lipids and lipid-modifying drug target genes with atrial fibrillation risk based on genomic data.

Lipids in health and disease - 8 Jun 2024

Tao Yuhang, Wang Yuxing, Yin Yongkun, Zhang Kai, Gong Yingchao, Ying Hangying, Jiang Ruhong

Abstract excerpt

BACKGROUND: The causal associations of lipids and the drug target genes with atrial fibrillation (AF) risk remain obscure. We aimed to investigate the causal associations using genetic evidence. METHODS: Mendelian randomization (MR) analyses were conducted using summary-level genome-wide association studies (GWASs) in European and East Asian populations. Lipid profiles (low-density lipoprotein cholesterol,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38851763
DOI: 10.1186/s12944-024-02163-4
PMCID: PMC11161942

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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