Article
Causal effects of plasma lipids on the risk of atrial fibrillation: A multivariable mendelian randomization study.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 6 May 2021
Jiang Qi, Qin Dingxin, Yang Ling, Lin Yongping, Zhai Lishang, Zhang Yuli, Yang Gang, Wang Kexin, Tong Debing, Li Xintao, Chen Zijun, Huang Kai, Yu Tianhong, Xiang Xue, Cui Chang, Cai Cheng, Shi Jiaojiao, Li Mingfang, Chen Minglong
Abstract excerpt
BACKGROUND AND AIMS: Observational studies have suggested that plasma lipids contribute substantially to cardiovascular disease, but "cholesterol paradox" in atrial fibrillation (AF) remains. We sought to investigate the causal effects of lipid profiles on the risk of AF. METHODS AND RESULTS: Two-sample Mendelian randomization (MR) framework was implemented to examine the causality of association. Summary...
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