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Article

Kinematic analysis of kinases and their oncogenic mutations - Kinases and their mutation kinematic analysis.

Molecular informatics - 1 Jun 2024

Chen Xiyu, Leyendecker Sigrid

Abstract excerpt

Protein kinases are crucial cellular enzymes that facilitate the transfer of phosphates from adenosine triphosphate (ATP) to their substrates, thereby regulating numerous cellular activities. Dysfunctional kinase activity often leads to oncogenic conditions. Chosen by using structural similarity to 5UG9, we selected 79 crystal structures from the PDB and based on the position of the phenylalanine side chain in...

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PMID: 38850084
DOI: 10.1002/minf.202300250

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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