Article
Exploring CYP2D6 polymorphisms and angiotensin receptor blocker response in the Bai hypertensive population.
Pharmacogenetics and genomics - 1 Aug 2024
Yang Canbiao, Zhang Guoqiang, Shu Chang, Lv Linxi, Liu Zhengxing, Tian Yan, Tan Qi, Wang Zhaobin, Hu Songnian, Yang Libo, Sun Ningling
Abstract excerpt
OBJECTIVE: The CYP2D6 enzyme is crucial for the metabolism and disposition of a variety of drugs. This study was conducted to examine the relationship between CYP2D6 gene polymorphisms and the response to angiotensin receptor blocker (ARB)-based treatment in patients of Chinese Bai ethnicity with hypertension. METHODS: Seventy-two hypertensive adults from the Chinese Bai ethnic group, exhibiting systolic blood...
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